Objective:To explore the effect and influencing factors of customized sound on tinnitus. Method:Result:The THI score decreased at the 1, 2, 3, 4, 5 and 6 months after treatment (P<0.01), compared with that before treatment. Gender, tinnitus type and presence or absence of voice allergy had no effect on THI score before treatment and 6 months after treatment (P>0.05). Conclusion:Customized sound therapy can reduce the score of THI in tinnitus patients, which supports that sound therapy can reduce the negative impact and disturbances produced by tinnitus, and its curative effect is not affected by gender, tinnitus type and presence or absence of voice allergy..