Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage.
Journal: 1985/March - British medical journal (Clinical research ed.)
ISSN: 0267-0623
PUBMED: 3917814
Abstract:
The intake of anti-inflammatory drugs by 268 patients with colonic or small bowel perforation or haemorrhage was compared with that by a group of patients, matched for age and sex, with uncomplicated lower bowel disease. Patients with perforation or haemorrhage were more than twice as likely to be takers of anti-inflammatory drugs, but no association was detected with the intake of other types of drugs, particularly cardiovascular drugs. The association between complicated lower bowel disease and intake of anti-inflammatory drugs may be causal.
Relations:
Content
Citations
(83)
References
(6)
Diseases
(2)
Conditions
(1)
Chemicals
(3)
Organisms
(1)
Anatomy
(1)
Similar articles
Articles by the same authors
Discussion board
Br Med J (Clin Res Ed) 290(6465): 347-349

Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage.

Abstract

The intake of anti-inflammatory drugs by 268 patients with colonic or small bowel perforation or haemorrhage was compared with that by a group of patients, matched for age and sex, with uncomplicated lower bowel disease. Patients with perforation or haemorrhage were more than twice as likely to be takers of anti-inflammatory drugs, but no association was detected with the intake of other types of drugs, particularly cardiovascular drugs. The association between complicated lower bowel disease and intake of anti-inflammatory drugs may be causal.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (716K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Davies DR, Brightmore T. Idiopathic and drug-induced ulceration of the small intestine. Br J Surg. 1970 Feb;57(2):134–139. [PubMed] [Google Scholar]
  • Schwartz HA. Lower gastrointestinal side effects of nonsteroidal antiinflammatory drugs. J Rheumatol. 1981 Nov-Dec;8(6):952–954. [PubMed] [Google Scholar]
  • Coutrot S, Roland D, Barbier J, Van Der Marcq P, Alcalay M, Matuchansky C. Acute perforation of colonic diverticula associated with short-term indomethacin. Lancet. 1978 Nov 11;2(8098):1055–1056. [PubMed] [Google Scholar]
  • Sturges HF, Krone CL. Ulceration and stricture of the jejunum in a patient on long-term indomethacin therapy. Am J Gastroenterol. 1973 Feb;59(2):162–169. [PubMed] [Google Scholar]
  • Miettinen O. Estimability and estimation in case-referent studies. Am J Epidemiol. 1976 Feb;103(2):226–235. [PubMed] [Google Scholar]
  • Coggon D, Langman MJ, Spiegelhalter D. Aspirin, paracetamol, and haematemesis and melaena. Gut. 1982 Apr;23(4):340–344.[PMC free article] [PubMed] [Google Scholar]
Abstract
The intake of anti-inflammatory drugs by 268 patients with colonic or small bowel perforation or haemorrhage was compared with that by a group of patients, matched for age and sex, with uncomplicated lower bowel disease. Patients with perforation or haemorrhage were more than twice as likely to be takers of anti-inflammatory drugs, but no association was detected with the intake of other types of drugs, particularly cardiovascular drugs. The association between complicated lower bowel disease and intake of anti-inflammatory drugs may be causal.
Collaboration tool especially designed for Life Science professionals.Drag-and-drop any entity to your messages.