Abstract:

The SARS‐CoV‐2 pandemic has led to worldwide research aiming to identify the risk factors for developing critical illness and mortality caused by COVID‐19. It quickly became apparent that besides older age, obesity is one of the most important risk factors for a more severe course of COVID‐19, although the mechanisms remain largely unknown [1‐3]. Notably, with respect to acute respiratory distress syndrome (ARDS) and acute lung injury (ALI), evidence is mounting that obesity is a risk factor for ARDS/ALI, but among people with ARDS/ALI, obesity is associated with better outcome, a phenomenon which has been called the “obesity paradox” [4,5].

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Obesity, adipokines and COVID‐19

Adrian Post

Stephan Bakker

Robin Dullaart

^{Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen the Netherlands,}

Adrian Post, Email: ln.gcmu@10tsop.a.

^{Corresponding author.}

^{Corresponding author}
Adrian Post, Department of Internal Medicine, University Medical Center Groningen, 9700 RB Groningen, the Netherlands
Email: ln.gcmu@10tsop.a,

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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