Three new inositol angelate compounds (<b>1-3</b>) and two new tirucallane-type alkaloids (<b>4</b> and <b>5</b>) were isolated from the <i>Amoora dasyclada</i>, and their structures were established mainly by means of combination of 1D and 2D nuclear magnetic resonance and HR-ESI-MS. Based on cytotoxicity testing, compounds <b>4</b> and <b>5</b> exhibited significant cytotoxic activity against human cancer cell line HepG2 with IC₅₀ value at 8.4 and 13.2 μM. In addition, compounds <b>4</b> and <b>5</b> also showed remarkable growth inhibitory activity to <i>Artemia salina</i> larvae.