Sida cordifolia extracts of the aerial and root parts showed good analgesic, antiinflammatory and hypoglycaemic activities. The ethyl acetate (EA) extract of root (SCR-E) showed comparable antiinflammatory activity with indomethacin and possessed significantly higher activity when compared with that of the methanol extract of the root part (SCR-M). The ethyl acetate extract of both root and aerial parts of Sida cordifolia (SCR-E and SCA-E) showed very good central and peripheral analgesic activities at a dose of 600 mg/kg. The methanol extract of root (SCR-M) was found to possess significant hypoglycaemic activity.