Indian J Otolaryngol Head Neck Surg 49(Suppl 1): 63-66
Tinnitus: Our experience with intratympanic instillation of 2% Xylocaine
Abstract
Idiopathic subjective tinnitus is quite an obscure otopathology for over the decades. This paper deals with the results of an intratympanic instillation of 2% Xylocaine through Grommet over a six weeks time. Patients overall compliance was 26%. We suggest this method of treatment for those who have been treated unsuccessfully with drugs, acupuncture, electrical control, biofeedback etc with not much reward. Patient is warned about impending nausea and vomiting. Tinnitus is alleviated to cope with near to normal life.
Abstract
Idiopathic subjective tinnitus is quite an obscure otopathology for over the decades. This paper deals with the results of an intratympanic instillation of 2% Xylocaine through Grommet over a six weeks time. Patients overall compliance was 26%. We suggest this method of treatment for those who have been treated unsuccessfully with drugs, acupuncture, electrical control, biofeedback etc with not much reward. Patient is warned about impending nausea and vomiting. Tinnitus is alleviated to cope with near to normal life.
Key words: Idiopathic subjective tinnitus (IST), Xylocaine 2% Intratympanic instillation
Full Text
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
1. Arnsdorf M F, Bigger J. T. Effect of lidocaine hydrochloride on membrane conducutance in mammalian cardiac purkinjee fibres. Journal of Clinical Investigation. 1972;Sl:2252–2263. doi: 10.1172/JCI107034. [PubMed] [CrossRef] [Google Scholar]
2. Bernard C H, Bohm E. On the central effects of Xylocaine with special reference to its influence on epileptic phenomena. Acta Physiologica Scandinevia. 1954;31(114):5–6.[Google Scholar]
3. Chung D Y, Ganon R P, Mason L. Factors affecting the prevalence of tinnitus. Radilogy. 1984;23:441–452.[Google Scholar]
4. Englesson s, Larsson B, Lindquist N G. Accumulation of 14 C lidocaine in the inner ear. Acta Otolaryngologica. 1976;82:297–300. doi: 10.3109/00016487609120910. [CrossRef] [Google Scholar]
5. Fisch U. Transtemporal surgery of internal auditory canal; Report of 92 cases, techniques, indications and results. Advances in Otolaryngology. 1970;17:203–224.[Google Scholar]
6. Fradis M, Podoshin L, Ben David J, Reiner B. Treatment of Meniere’s disease by intratympanic injection with lidocaine. Archives of Otolaryngology. 1985;111:491–493. [PubMed] [Google Scholar]
7. Gerjot T. Intravenous Xylocaine in treatment of attacks of Meniere’s disease. Acta Otolaryngologica. 1976;80(188):190–195.[Google Scholar]
8. Goodhill V. (1979): Ear disease, deafness, dizziness. Harper and Row publishers pp-731–739.
9. Israel J M, Connelly T S, McTique S T. Lignocaine in treatment of tinnitus auris. Archives of Otolaryngology. 1982;108:371–473.[Google Scholar]
10. Hulshof Jan H, Vermeji Peter. Effect of intravenous lidocaine and several different doses of oral tocainide HCL on tinnitus: A dose finding study. Acta Otolaryngologica. 1984;98:231–238. doi: 10.3109/00016488409107559. [CrossRef] [Google Scholar]
11. Jovel E, Mouncy D F, McGee J A. Auditory brain stem response during systemic infusion of lidocaine. Archives of Otolaryngology. 1982;108:71–76. [PubMed] [Google Scholar]
12. Letchenberg R, Shulman A (1984): Benzodiazepines in treatment of tinnitus. Journal of Laryngology and Otology (supplement 9) 271–276.
13. Okusa M, Shiraishi T, Maysunaga T. Tinnitus suppression by electrical stimulation in sensorineural deaf patients. Acta Otolaryngologica. 1993;501:554–58.[Google Scholar]
14. Podoshin L, Ben David Y, Fradis M (1991): Idiopathic symptomatic tinnitus treated by biofeedback, acupuncture and drug therapy.Ear, Nose, Throat Journal (in press)
15. Sakata E, Umeda V, Takahoshi K, Ohtsui K. Treatment of cochlear tinnitus; Blocking therapy with 4% xylocaine. Journal of Otolaryngology (Japan) 1976;79:741–745.[Google Scholar]
16. Shea J, Harell M. Management of tinnitus with lidocaine and carbamazepine. Laryngoscope. 1978;88:1477–1484. [PubMed] [Google Scholar]
17. Shulman A, Tonndorf J, Goldstien B. Electrical tinnitus control. Acta Otolaryngologica. 1985;99:318–325. doi: 10.3109/00016488509108916. [CrossRef] [Google Scholar]
References
- 1. Arnsdorf M F, Bigger J. T. Effect of lidocaine hydrochloride on membrane conducutance in mammalian cardiac purkinjee fibres. Journal of Clinical Investigation. 1972;Sl:2252–2263. doi: 10.1172/JCI107034.] [[PubMed]
- 2. Bernard C H, Bohm EOn the central effects of Xylocaine with special reference to its influence on epileptic phenomena. Acta Physiologica Scandinevia. 1954;31(114):5–6.[PubMed][Google Scholar]
- 3. Chung D Y, Ganon R P, Mason LFactors affecting the prevalence of tinnitus. Radilogy. 1984;23:441–452.[PubMed][Google Scholar]
- 4. Englesson s, Larsson B, Lindquist N GAccumulation of 14 C lidocaine in the inner ear. Acta Otolaryngologica. 1976;82:297–300. doi: 10.3109/00016487609120910.[PubMed][Google Scholar]
- 5. Fisch UTranstemporal surgery of internal auditory canal; Report of 92 cases, techniques, indications and results. Advances in Otolaryngology. 1970;17:203–224.[PubMed][Google Scholar]
- 6. Fradis M, Podoshin L, Ben David J, Reiner BTreatment of Meniere’s disease by intratympanic injection with lidocaine. Archives of Otolaryngology. 1985;111:491–493.[PubMed][Google Scholar]
- 7. Gerjot TIntravenous Xylocaine in treatment of attacks of Meniere’s disease. Acta Otolaryngologica. 1976;80(188):190–195.[PubMed][Google Scholar]
- 8. Goodhill V. (1979): Ear disease, deafness, dizziness. Harper and Row publishers pp-731–739.
- 9. Israel J M, Connelly T S, McTique S TLignocaine in treatment of tinnitus auris. Archives of Otolaryngology. 1982;108:371–473.[PubMed][Google Scholar]
- 10. Hulshof Jan H, Vermeji PeterEffect of intravenous lidocaine and several different doses of oral tocainide HCL on tinnitus: A dose finding study. Acta Otolaryngologica. 1984;98:231–238. doi: 10.3109/00016488409107559.[PubMed][Google Scholar]
- 11. Jovel E, Mouncy D F, McGee J AAuditory brain stem response during systemic infusion of lidocaine. Archives of Otolaryngology. 1982;108:71–76.[PubMed][Google Scholar]
- 12. Letchenberg R, Shulman A (1984): Benzodiazepines in treatment of tinnitusJournal of Laryngology and Otology (supplement 9) 271–276.
- 13. Okusa M, Shiraishi T, Maysunaga TTinnitus suppression by electrical stimulation in sensorineural deaf patients. Acta Otolaryngologica. 1993;501:554–58.[PubMed][Google Scholar]
- 14. Podoshin L, Ben David Y, Fradis M (1991): Idiopathic symptomatic tinnitus treated by biofeedback, acupuncture and drug therapy.Ear, Nose, Throat Journal (in press)
- 15. Sakata E, Umeda V, Takahoshi K, Ohtsui KTreatment of cochlear tinnitus; Blocking therapy with 4% xylocaine. Journal of Otolaryngology (Japan) 1976;79:741–745.[PubMed][Google Scholar]
- 16. Shea J, Harell MManagement of tinnitus with lidocaine and carbamazepine. Laryngoscope. 1978;88:1477–1484.[PubMed][Google Scholar]
- 17. Shulman A, Tonndorf J, Goldstien BElectrical tinnitus control. Acta Otolaryngologica. 1985;99:318–325. doi: 10.3109/00016488509108916.[PubMed][Google Scholar]