Fourteen dogs with pancreatic degenerative atrophy (PDA) were fed their original diets or a special diet for 2 periods of 4 weeks to compare the severity of clinical signs in relation to different types of diet. During the first period, the dogs were given ordinary food, and in the second period, the dogs were given only the special diet that consisted of a commercial moderate-fat, low-fiber, highly-digestible food. In addition, equal amounts of pancreatic enzymes were added into the food during highly-digestible food. In addition, equal amounts of pancreatic enzymes were added into the food during both periods. The owners were given a questionnaire covering 9 typical signs of PDA. They were asked to assess the severity of signs daily for the 2 periods using a scale provided with the questionnaire. The general well-being of the dogs was significantly (p less than 0.05) better during the period when the dogs were fed a special diet. Of the individual clinical signs associated with PDA the severity of flatulence, borborygmi, volume of faeces and frequency of defecation were significantly (p less than 0.05) decreased on the special diet. There were no significant differences in appetite, drinking, colour and consistency of the faeces or in coprophagy between the 2 feeding periods. The costs of the special diet were almost double compared to the ordinary diets.