A total of 750 pregnant women were examined by the blind screening method at terms of 7-16, 18-24, 28-36, 38-41 weeks and on day 2 after delivery. A high and medium-high reliable correlation between the laboratory instrumental parameters characterizing vascular disorders and pathological weight gain, symptoms of vascular dysfunction, transitory edema and proteinuria has been revealed. These symptoms were shown to occur not only in gestoses, but in cases with small-for-date fetuses, early detachment of normally positioned placenta, miscarriages, and prolonged gestation. Qualitative characteristics and time course of the studied symptoms in women with different course of gestation are presented. Early course of pathological gestation complicated by gestosis, small-for-date fetus, miscarriage, prolonged pregnancy, and preterm detachment of normal placenta is defined as the vascular syndrome of pregnancy.