Isolation of inhibitors of TPA-induced mouse ear edema from Hoelen, Poria cocos.
Journal: 1996/August - Chemical and Pharmaceutical Bulletin
ISSN: 0009-2363
PUBMED: 8681415
Abstract:
Triterpene carboxylic acids were isolated from the methanol extract of Hoelen, Poria cocos, and found to inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema. Their chemical structures were identified as 3 beta,-16 alpha-dihydroxylanosta-7,9(11),24-trien-21-oic acid, 16 alpha-hydroxydehydropachymic acid, 16 alpha-hydroxytrametenolic acid and dehydrotumulosic acid.
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