Aim
This study aims to test the tensile strength and growth of
Candida albicans on Viscogel tissue conditioner when incorporated with coconut oil (CCO) and to compare its efficacy with other antifungal agents.
Settings and Design
Evaluative -
In-vitro study design.
Materials and Methods
Fifty dumbbell-shaped samples (
n = 10) of Viscogel tissue conditioner were fabricated according to ASTM standard and were classified into 5 groups (10% CCO, 30% w/w tea tree oil, 5% w/w fluconazole, 0.03% w/w silver nanoparticles, and plain tissue conditioner). These samples were compared and evaluated for their tensile strength. Further to test the antifungal activity, a total of 60 samples (
n = 15) were fabricated, each group (
n = 15) was further divided into three subgroups (
n = 5), namely 24-h, 3-day, and 5-day period, which were inoculated in sabouraud dextrose agar plate to test for the growth of
C. albicans.
Statistical Analysis Used
Oneway ANOVA and
post hoc Tukey honestly significant difference test.
Results
C. albicans on the 5
th day.
Conclusions
C. albicans, and addition of the same increased the tensile strength of the tissue conditioner.