The present work is a study with the objective of learning the conceptions of the patient bearer of acute myeloid leukemia (AML) concerning to fatigue symptoms and their repercussions in his/her daily life as well as the actions performed in order to minimize the fatigue. It is a descriptive and exploratory study of qualitative character carried out with hospitalized patients. Eight (8) adult subjects with diagnosis of AML were interviewed. The data were examined according to the technique of content analysis. The results found led to the elaboration of three categories: Conceptions regarding fatigue, Change in lifestyle and Actions taken in order to minimize fatigue. It was concluded that it is possible to identify the fatigue dimension in the daily life of these patients and also optimize measures in order to minimize this symptom. We recommend to health professionals a better understanding of fatigue in order to provide better care so that it is possible to guarantee a higher quality of life for these patients.