Intervention action of total flavonoids from root of <em>Ilex pubescens</em> in cerebral ischemic tolerance with blood stasis
Note, compared with cerebral ischemia reperfusion injury group P < 0.05 P < 0.01, compared with cerebral ischemic tolerance group P < 0.05 P < 0.01, compared with non-blood stasis sham operation group P < 0.05 P < 0.01.
Note, compared with cerebral ischemia reperfusion injury group P < 0.05 P < 0.01, compared with cerebral ischemic tolerance group P < 0.05 P < 0.01.
Note, “–” Brain nerve cell membrane, cytoplasmic Bcl-2, Bax negative,“+” Brain nerve cell membrane, cytoplasmic Bcl-2, Bax weakly positive, “++” Brain nerve cell membrane, cytoplasmic Bcl-2, Bax positive,“+++” Brain nerve cell membrane, cytoplasmic Bcl-2, Bax strongly positive.
Note, “–” Brain nerve cells are normal, the cell cytoplasm is rich, the nucleus and the nucleus are clearly visible. “+” 20% Brain nerve cells showed a shrinking phenomenon, the individual cells are eosinophilic change. “++” 50% Brain nerve cells showed atrophy, with eosinophilic degeneration, individual cell showed vacuolar degeneration. “+++” 80% Brain nerve cells showed atrophy, with eosinophilic degeneration and vacuolar degeneration.
Footnotes
Peer review under responsibility of King Saud University.