Light and mechanical injury are the two most important environmental factors which stimulate postharvest glycoalkaloid synthesis in potato tubers. Partial control of light-induced glycoalkaloid formation has been achieved by treating potato tubers with some chemicals as Ethephon, Alar, Phosphon, Phosphon-S, Amchem 72-A42, Amchem 70-334, Nemagon, Telone, detergents, surfactants, control-atmosphere storage and subatmospheric pressure storage. Complete inhibition of light-induced glycoalkaloid formation can only be obtained by hot wax coating, oil coating, vacuum packaging and anoxia water submersion. Treatment with isopropyl-N-(3-chlorophenyl)-carbamate and gamma-irradiation effectively control wound-induced glycoalkaloid formation of potato tubers.