The case of primary oat-cell carcinom of the larynx with metastases in the thyreoid gland and paratracheal lymphnodes is reported on. The different methods of treatment are examined, used examples of the much more common oat-cell carcinoma of the lung. The applicability of the methods to oat-cell carcinoma of the larynx is discussed. Our treatment scheme of surgery and extended radiation is used if the tumor is known to be locally restricted.