In this article, we tried to take stock of the state of the art in ultrasonic-assisted lipoplasty focusing on its most recent technologic advances and in the newest clinical applications, such as overweight, obesity, breast surgery and regenerative medicine. Great space was devoted to the analysis and clarification of the most common myths and legends related to this intriguing technique.

Keywords: Adipose-derived stem cells (ADSCs); Liposuction (SAL); Obesity; Ultrasonic mega lipoplasty (UML); Ultrasonic-assisted lipoplasty (UAL).