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Publication
Journal: Psychophysiology
June/14/2017
Abstract
Blind source separation (BSS) based artifact rejection systems have been extensively studied in the electroencephalogram (EEG) literature. Although there have been advances in the development of techniques capable of dissociating neural and artifactual activity, these are still not perfect. As a result, a compromise between reduction of noise and leakage of neural activity has to be found. Here, we propose a new methodology to enhance the performance of existing BSS systems: Localized component filtering (LCF). In essence, LCF identifies the artifactual time segments within each component extracted by BSS and restricts the processing of components to these segments, therefore reducing neural leakage. We show that LCF can substantially reduce the neural leakage, increasing the true acceptance rate by 22 percentage points while worsening the false acceptance rate by less than 2 percentage points in a dataset consisting of simulated EEG data (4% improvement of the correlation between original and cleaned signals). Evaluated on real EEG data, we observed a significant increase of the signal-to-noise ratio of up to 9%.
Publication
Journal: Journal of Oral Rehabilitation
February/14/2019
Abstract
It is considered important to evaluate the ability to control lip-closing force (LCF).This study aimed to investigate the ability to control directional LCF.The experimental system included an apparatus developed to measure LCF during lip pursing in eight directions (upper, lower, right, left and the four directions in between) and a display showing the exerted LCF and a target value in each direction in real time. Twenty subjects (10 men and 10 women) were instructed to maintain the LCF at a specific target value using visual feedback. Based on our preliminary experiments, the target value was set as 50% of the maximum LCF, and the range was set at the target value ±8%. The accuracy rate was defined as the ratio of the matched time, in which the subject was able to keep the LCF in the target range, to the total 3 seconds.The accuracy rate of men was higher than in women in the lower, lower left and lower right directions. The accuracy rate of the directional LCF differed significantly depending on the direction. In assessing the accuracy rate for each directional LCF, the rates of upper and lower directional LCF were significantly higher than those of oblique directional LCF. No significant relationship was observed between the accuracy rate and the maximum LCF except for one direction in men subjects.Our findings suggest that the ability to control directional LCF is affected by sex and the force direction.
Publication
Journal: Environmental Science & Technology
November/5/2009
Abstract
California's low carbon fuel standard (LCFS) was designed to incentivize a diverse array of available strategies for reducing transportation greenhouse gas (GHG) emissions. It provides strong incentives for fuels with lower GHG emissions, while explicitly requiring a 10% reduction in California's transportation fuel GHG intensity by 2020. This paper investigates the potential for cost-effective GHG reductions from electrification and expanded use of biofuels. The analysis indicates that fuel providers could meetthe standard using a portfolio approach that employs both biofuels and electricity, which would reduce the risks and uncertainties associated with the progress of cellulosic and battery technologies, feedstock prices, land availability, and the sustainability of the various compliance approaches. Our analysis is based on the details of California's development of an LCFS; however, this research approach could be generalizable to a national U.S. standard and to similar programs in Europe and Canada.
Publication
Journal: Sensors
March/5/2018
Abstract
Power transmission line icing (PTLI) problems, which cause tremendous damage to the power grids, has drawn much attention. Existing three-dimensional measurement methods based on binocular stereo vision was recently introduced to measure the ice thickness in PTLI, but failed to meet requirements of practical applications due to inefficient keypoint matching in the complex PTLI scene. In this paper, a new keypoint matching method is proposed based on the local multi-layer convolutional neural network (CNN) features, termed Local Convolutional Features (LCFs). LCFs are deployed to extract more discriminative features than the conventional CNNs. Particularly in LCFs, a multi-layer features fusion scheme is exploited to boost the matching performance. Together with a location constraint method, the correspondence of neighboring keypoints is further refined. Our approach achieves 1.5%, 5.3%, 13.1%, 27.3% improvement in the average matching precision compared with SIFT, SURF, ORB and MatchNet on the public Middlebury dataset, and the measurement accuracy of ice thickness can reach 90.9% compared with manual measurement on the collected PTLI dataset.
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Publication
Journal: Medical Dosimetry
September/15/1997
Abstract
Differences between the scatter conditions of dosimetry and treatment situation are more important in the case of large-field photon beams than in standard ones. In the former, the scattering volume is defined by the phantom cross section; in the latter, the radiation field size. Two factors should be considered: the thickness and the cross section of the phantom. Both of them have an effect on the Percentage Depth Dose (PDD) distribution. In a previous study we addressed the influence of backscatter thickness on dose delivered. The aim of this work is to measure the effect of cross section phantom on the PDD curves under our TBI treatment conditions. Results showed a strong dependence of the PDDs on this parameter. A semi-empirical expression has also been derived to calculate (within 0.5% uncertainty) the Lateral scatter Correction Factor (LCF). The model of LCF states a linear dependence on depth whilst slope of these curves depends exponentially on distance to the lateral surface. The algorithm is being applied to our practical Total Body Irradiation (TBI) procedure.
Publication
Journal: Artificial Organs
January/26/2017
Abstract
The aim of this work is to develop and test a lumped parameter model of the cardiovascular system to simulate the concurrent use of pulsatile (PVAD) and continuous flow (CVAD) ventricular assist device (VAD) on Fontan patients. Echocardiographic and hemodynamic data of five Fontan patients were retrospectively collected and used to simulate the patients' baseline hemodynamics. Then, for each patient, the following assistance modality was simulated for the cavopulmonary and the single ventricle (SV): (a) CVAD for cavopulmonary assistance (RCF) and PVAD assisting the SV (LCF) (RPF + LCF), (b) CVAD assisting SV and PVAD for cavopulmonary assistance (LPF + RCF). The numerical model can well reproduce patients' baseline. The cardiac output increases more importantly in the LCF + RPF configuration (35 vs. 8%). Ventricular volume decreases more evidently in the configuration LCF + RPF (28 vs. 6%), atrial pressure decreases in the LCF + RPF modality (10%), while it slightly increases in the RCF + LPF modality. The pulmonary arterial pressure slightly decreases (increases) in the configuration RCF + LPF (LCF + RPF). Ventricular external work increases in both configurations because of the total increment of the cardiac output. However, artero-ventricular coupling improves in both configurations: RCF + LPF-14%, LCF + RPF-41%. The pulsatility index decreases (increases) by 8% (13.8%) in the configuration LCF + RPF (RCF + LPF). A model could permit us to simulate extreme physiological conditions of the implantation of both CF and PF VAD on the Fontan patient and could permit to choose the proper VAD on the base of patients' condition. The configuration LCF + RPF seems to maximize the hemodynamic benefits.
Publication
Journal: Journal of Oral Rehabilitation
May/10/2015
Abstract
The objectives of this study were to quantitatively evaluate the relationship between frontal craniofacial morphology and the horizontal balance of the lip-closing forces (LCF) generated during maximum voluntary pursing-like movements in patients with mandibular deviation. Thirty-one subjects (median age 25·4 ± 8·9 years) without a history of orthodontic treatment were randomly selected from among the orthodontic patients who visited our hospital. Lip-closing forces was recorded in eight directions during maximum voluntary pursing-like lip-closing movements. The subjects were divided into the deviation (two males and 11 females) and non-deviation groups (four males and 14 females). There was no significant difference in the total LCF between the deviation and non-deviation groups. In the deviation group, the mean LCF value on the deviation side of the upper lip was significantly lower than that detected on the non-deviation side of the upper lip, while the mean LCF value for the deviation side of the lower lip was significantly higher than that for the non-deviation side of the lower lip. In contrast, no significant difference in upper or lower lip LCF was detected between the deviation and non-deviation sides in the non-deviation group. The difference in the LCF generated in the lower lip between the deviation and non-deviation sides was significantly positively correlated with mandibular menton deviation and significantly negatively correlated with the difference in maxillary height between the deviation and non-deviation sides. These results suggest that the horizontal balance of the upper and lower lip LCF produced during pursing-like lip-closing movements in patients with mandibular deviation is related to frontal craniofacial morphology.
Publication
Journal: Faraday Discussions
October/17/2016
Abstract
Four types of synthetic sorbents were developed for high-temperature post-combustion calcium looping CO2 capture using Longcal limestone. Pellets were prepared with: lime and cement (LC); lime and flour (LF); lime, cement and flour (LCF); and lime, cement and flour doped with seawater (LCFSW). Flour was used as a templating material. All samples underwent 20 cycles in a TGA under two different calcination conditions. Moreover, the prepared sorbents were tested for 10 carbonation/calcination cycles in a 68 mm-internal-diameter bubbling fluidized bed (BFB) in three environments: with no sulphur and no steam; in the presence of sulphur; and with steam. When compared to limestone, all the synthetic sorbents exhibited enhanced CO2 capture performance in the BFB experiments, with the exception of the sample doped with seawater. In the BFB tests, the addition of cement binder during the pelletisation process resulted in the increase of CO2 capture capacity from 0.08 g CO2 per g sorbent (LF) to 0.15 g CO2 per g sorbent (LCF) by the 10th cycle. The CO2 uptake in the presence of SO2 dramatically declined by the 10th cycle; for example, from 0.22 g CO2 per g sorbent to 0.05 g CO2 per g sorbent in the case of the untemplated material (LC). However, as expected all samples showed improved performance in the presence of steam, and the decay of reactivity during the cycles was less pronounced. Nevertheless, in the BFB environment, the templated pellets showed poorer CO2 capture performance. This is presumably because of material loss due to attrition under the FB conditions. By contrast, the templated materials performed better than untemplated materials under TGA conditions. This indicates that the reduction of attrition is critical when employing templated materials in realistic systems with FB reactors.
Publication
Journal: Health Physics
August/16/1989
Abstract
As a continuation of previous research on worst case transportation accidents involving radioactive material (Dodd and Humphries 1988a), and protective action guidance for radioactive material transportation accidents (Dodd and Humphries 1988b), this paper describes the risks from such accidents in Oregon. Radioactive material transportation risks are defined in terms of accident consequences multiplied by the accident probabilities and are expressed as latent cancer fatalities (LCFs). For each of 17 different shipment types, five dose contributions are summed and multiplied by the population density and accident probability. The five dose contributors considered are: inhalation, resuspension, cloudshine, groundshine and direct exposure. The variables over which each of these dose contributors are integrated include seven accident severity categories, three population density zones, five regions of the state, as well as many isopleth areas and radionuclides. Allowance is also made for the possible distribution of meteorological conditions in each area. The dose to the public, emergency responders, pedestrians and personnel in other traffic are all considered. It is concluded that the current level of risk is 1.2 X 10(-5) latent cancer fatalities per year in Oregon. This is equivalent to one LCF every 83,000 y. This compares to 1.2 non-radiological fatalities associated from the same shipments.
Publication
Journal: Immunology today
December/8/1996
Publication
Journal: Chemical Record
July/12/2010
Abstract
Leguminous plants open their leaves during the daytime and close them at night as if sleeping, a type of movement that follows circadian rhythms, and is known as nyctinastic movement. This phenomenon is controlled by two endogenous bioactive substances that exhibit opposing activities: Leaf-Opening Factor (LOF), which opens the leaves, and Leaf-Closing Factor (LCF), which closes them. The authors have carried out chemical biological research using these bioactive substances as molecular probes in order to clarify the mechanisms of nyctinastic movement. Here, we report on the detection and identification of the target proteins of these compounds using original methodology.
Publication
Journal: Journal of Environmental Management
February/25/2009
Abstract
Modelling land cover change from existing land cover maps is a vital requirement for anyone wishing to understand how the landscape may change in the future. In order to test any land cover change model, existing data must be used. However, often it is not known which data should be applied to the problem, or whether relationships exist within and between complex datasets. Here we have developed and tested a model that applied evolutionary processes to Bayesian networks. The model was developed and tested on a dataset containing land cover information and environmental data, in order to show that decisions about which datasets should be used could be made automatically. Bayesian networks are amenable to evolutionary methods as they can be easily described using a binary string to which crossover and mutation operations can be applied. The method, developed to allow comparison with standard Bayesian network development software, was proved capable of carrying out a rapid and effective search of the space of possible networks in order to find an optimal or near-optimal solution for the selection of datasets that have causal links with one another. Comparison of land cover mapping in the North-East of Scotland was made with a commercial Bayesian software package, with the evolutionary method being shown to provide greater flexibility in its ability to adapt to incorporate/utilise available evidence/knowledge and develop effective and accurate network structures, at the cost of requiring additional computer programming skills. The dataset used to develop the models included GIS-based data taken from the Land Cover for Scotland 1988 (LCS88), Land Capability for Forestry (LCF), Land Capability for Agriculture (LCA), the soil map of Scotland and additional climatic variables.
Publication
Journal: Heliyon
November/5/2019
Abstract
This study presents the properties of a recycled aggregate geopolymer mortar made with a blend of high-calcium fly ash (HCF) and low-calcium fly ash (LCF). An experimental study was divided into two series. In series I, an effort was made to produce a more durable HCF geopolymer by partially replacing a portion of the HCF with LCF. A mortar with a 50:50 weight blend of HCF and LCF provided a high early strength and showed excellent potential in an acidic environment. In series II, recycled aggregate was used in the LCF-blended HCF geopolymer mortar. The results showed that the compressive strength of the geopolymer mortar decreased with an increase in the recycled aggregate content. The results also indicated that application of the mortar made with recycled aggregate under aggressive conditions should be avoided. However, a mixture with 25% recycled aggregate showed a compressive strength similar to that of the control mixture containing 100% natural aggregate.
Publication
Journal: Journal of Rehabilitation Medicine
November/20/2017
Abstract
OBJECTIVE
To determine whether early mobilization of patients with severe acquired brain injury, performed in the intensive/neurointensive care unit, influences functional outcome.
METHODS
Prospective observational study.
METHODS
Fourteen centres in Italy.
METHODS
A total of 103 consecutive patients with acquired brain injury.
METHODS
Clinical, neurological and functional data, including the Glasgow Coma Scale (GCS), Disability Rating Scale (DRS), the Rancho Los Amigos Levels of Cognitive Functioning (LCF), Early Rehabilitation Barthel Index (ERBI), Glasgow Outcome Scale (GOS), and Functional Independence Measure (FIM) were collected at admission and every 3?5 days until discharge from the intensive/neurointensive care unit. Patients were divided into mobilization and no mobilization groups, depending on whether they received mobilization. Data were analysed by intragroup and intergroup analysis using a multilevel regression model.
RESULTS
Sixty-eight patients were included in the mobilization group. At discharge, both groups showed significant improvements in GCS, DRS, LCF and ERBI scores. The mobilization group showed significantly better improvements in FIM cognitive, GOS and ERBI. The patients in the mobilization group stayed longer in the intensive care unit (p=0.01) and were more likely to be discharged to intensive rehabilitation at a significantly higher rate (p=0.002) than patients in the no mobilization group. No adverse events were reported in either group.
CONCLUSIONS
Early mobilization appears to favour the clinical and functional recovery of patients with severe acquired brain injury in the intensive care unit.
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Publication
Journal: Nursing Research
April/22/1992
Abstract
Dimensions of cognitive impairment that best discriminated between wandering and nonwandering ambulatory subjects were studied. Cognitive impairment was measured along four dimensions: abstract thinking, language, judgement, and spatial skills. Wanderers had higher overall levels of cognitive impairment and poorer performance on all cognitive dimensions. The dimension of language was the most important higher order cognitive skill differentiating wanderers from nonwanderers; basic cognitive skill deficits (memory, orientation, concentration) and medical bases of cognitive impairment also contributed to the distinction between the groups. Overall classification rates obtained by linear classification function (LCF) analyses were only slightly better than chance rates. However, LCF rates for nonwanderers ranged from 93% to 95%, suggesting greater homogeneity in the cognitive impairments specific to this group.
Authors
Publication
Journal: Retinal Cases and Brief Reports
September/23/2020
Abstract
Purpose: To report the clinical results of lens capsular flap (LCF) transplantation in a patient with refractory medium macular hole (MH).
Methods: Case report.
Results: A 66-year-old female myopic patient with a history of medium macular hole (MH) was previously unsuccessfully treated by vitrectomy surgery, internal limiting membrane (ILM) peeling and air-fluid exchange followed by 12% C2F6 tamponade into the vitreous cavity and face-down positioning. After the first surgery, the patient's visual acuity of the left eye remained only 20/400 on the Snellen scale, and a persistent medium MH (290 µm) was observed on optical coherence tomography. Cataract of the left eye was also noted. A second surgery, combined cataract-vitrectomy surgery, was carried out to seal the MH, performed under retrobulbar anesthesia. Because there was insufficient ILM tissue to perform the ILM flap procedure, we decided to use another technique involving an autologous LCF. The patient underwent LCF placement onto the MH along with gas tamponade. At 6 months, the MH was sealed, and the patient's vision had improved to 20/32 on the Snellen scale.
Conclusion: This is the first case report to describe the use of LCF to treat persistent medium MH. LCF seems to be effective in sealing small macular holes and was well tolerated by the patient.
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Publication
Journal: Basic Research in Cardiology
January/19/1982
Abstract
Chronically instrumented dogs were studied at rest and during exercise on two occasions 10--12 weeks apart. The left circumflex coronary artery (LCf) was initially constricted in all dogs. By the time of the second study the LCf was still patent in 9 dogs and had become occluded in 6. In the dogs with chronic coronary occlusion, collaterals restored myocardial flow to normal both at rest and during exercise, and there were no adverse hemodynamic effects when running. Conversely, in dogs with constricted but patent LCfs collateral development was inadequate to return ischemic flows to normal following transient coronary occlusion, and occlusion during exercise produced significant myocardial failure. Thus coronary collaterals can compensate for decreased antegrade coronary flow.
Publication
Journal: Biological Trace Element Research
June/21/2015
Abstract
To elucidate compositional changes of the ligament with aging, the authors investigated age-related changes of elements in the ligamentum capitis femoris (LCF) of monkeys with a wide range of ages by direct chemical analysis. Used rhesus and Japanese monkeys consisted of 9 males and 22 females, ranging in age from newborn to 31 years (average age = 10.4 ± 10.9 years). After incineration with nitric acid and perchloric acid, element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that the P content decreased significantly in the LCFs of monkeys with aging, but other six element contents, Ca, S, Mg, Zn, Fe, and Na, did not change significantly with aging. Assuming that the P content indicated the active cell density and the S content indicated the protein amount, an age-related change of the mass ratio of P/S was examined in the LCFs. The mass ratio of P/S decreased significantly in the LCFs in childhood. Regarding the relationships among elements, significant direct correlations were found among the Ca, P, S, and Mg contents in the LCFs. It was suggested that the active cell density of the connective tissue cells might decrease significantly in the LCF in childhood.
Publication
Journal: Antibiotics
June/1/2021
Abstract
Vulvovaginal candidiasis (VVC) and recurrencies are common in reproductive-aged women. The emergence of Candida strains resistant to conventional antimycotic drugs prompted the search for alternative therapies. Hyaluronic acid (HA), a uniform and linear glycosaminoglycan, has been proposed as an anti-Candida agent. Vaginal lactobacilli and their derivatives, including cell free culture supernatants (CFS), represent potential strategies for the treatment of Candida infections. In the present paper, the anti-Candida potential of HA and lyophilised CFS (LCFS), obtained from the vaginal strain Lactobacillus crispatus BC5, was investigated. HA and LCFS proved to be active towards a panel of clinical Candida isolates belonging to different species in a dose dependent manner and their association maintained the antifungal activity. Notably, also Candida species generally resistant to conventional antifungals resulted sensitive. A vaginal matrix based on microcrystalline cellulose and containing effective doses of both agents was developed and characterised. This vaginal formulation showed mucoadhesive ability and almost abrogated Candida albicans growth. In conclusion, HA and LCFS from L. crispatus BC5 are thus good candidates to design a new therapeutic strategy to counteract VVC, and the proposed vaginal matrix represents a promising prototype.
Keywords: Candida; Lactobacillus crispatus; hyaluronic acid; vaginal lactobacilli; vulvovaginal candidiasis.
Publication
Journal: Metallomics
June/7/2021
Abstract
The influence of morphology on the biological effects of nanomaterials (NMs) has not been well understood. In the present study, we compared the phytotoxicity of rod-shaped nano-cerium dioxide (R-CeO2) and nano-cerium phosphate (R-CePO4) to lettuce plants. The results showed that R-CeO2 significantly inhibited the root elongation of lettuce, induced oxidative damages, and caused cell death, while R-CePO4 was nontoxic to lettuce. The different distribution and speciation of Ce in plant tissues were determined by transmission electron microscopy (TEM) and X-ray absorption near edge spectroscopy (XANES) combined with linear combination fitting (LCF). The results showed that in the R-CeO2 group, part of Ce was transformed from Ce(IV) to Ce(III), while only Ce(III) was present in the R-CePO4 group. When interacting with plants, R-CeO2 is easier to be dissolved and transformed than R-CePO4, which might be the reason for their different phytotoxicity. Although they are both Ce-based NMs and have the same morphology, the toxicity of R-CeO2 seems to come from the released Ce3+ ions rather than its shape. This research emphasizes the importance of chemical composition and reactivity of nanomaterials to their toxicological effects.
Keywords: R-CeO2; R-CePO4; XANES; lettuce; phytotoxicity; transformation.
Publication
Journal: Neurological Sciences
October/14/2018
Abstract
BACKGROUND
The Brief Post-Coma Scale (BPCS) is an easy diagnostic tool for individuals with disorders of consciousness (DoC), in a reduced version from a previously Post-Coma Scale, that could distinguish patients in the minimally conscious state (MCS) from those in unresponsive wakefulness syndrome (UWS), formerly defined as vegetative state (VS).
OBJECTIVE
Aim of the study was to assess the diagnostic validity of the BPCS in comparison with the Coma Recovery Scale-Revised (CRS-R), in its Italian validated version, the Disability Rating Scale (DRS), the Level of Cognitive Functioning (LCF), and the Glasgow Outcome Scale (GOS).
METHODS
In an Italian multicenter study on 545 patients with DoC, 36 post-acute rehabilitation wards, 32 long-term care centers, and 2 family associations participated to data collection.
RESULTS
Statistically significant correlations were found between the BPCS and the other clinical scales: R = 0.586 (p < 0.001) with LCF, R = - 0.566 (p < 0.001) with DRS, R = 0.622 (p < 0.001) with CRS-R. The BPCS scores resulted significantly correlated with the time from acute event (R = 0.117, p = 0.006). Patients with GOS score 2 had mean BPCS of 1.84 ± 1.19, whereas those with GOS 3 had significantly higher scores 3.88 ± 1.71 (p < 0.001). Similarly, in patients with vegetative state/UWS (VS/UWS), the mean BPSC score was 1.71 ± 1.09, significantly lower (p < 0.001) than that of patients with minimally conscious state (BPCS = 3.83 ± 1.29). Finally, the agreement of the BPCS and clinical diagnosis was of 84.4%, with an odds ratio OR = 3.781 (95% CI = 3.026-4.725, p < 0.001).
CONCLUSIONS
The BPCS has demonstrated statistically significant correlations with the most commonly used scales in persons with DoC.
Publication
Journal: Review of Scientific Instruments
September/2/2020
Abstract
Innovative high-frequency magnetic sensors have been designed and manufactured in-house for installation on the Tokamak à Configuration Variable (TCV), which are now routinely operational during the TCV experimental campaigns. These sensors combine the Low Temperature Co-fired Ceramic (LTCC) and the classical thick-film technologies and are in various aspects similar to the majority of the in-vessel inductive magnetic sensors foreseen for ITER (around 450 out of the 505 currently being procured are of the LTCC-1D type). The TCV LTCC-3D magnetic sensors provide measurements in the frequency range up to 1 MHz of the perturbations to the wall-aligned toroidal (δBTOR), vertical (δBVER), and radial (δBRAD) magnetic field components. Knowledge of the equilibrium at the last closed flux-surface allows us to then obtain the field-aligned parallel (δBPAR ∼ δBTOR), poloidal (δBPOL), and normal (δBNOR) components, the latter being in most cases rather different from the vertical and radial components, respectively. The main design principles were aimed at increasing the effective area and reducing the self-inductance of the sensor in each of the three measurement axes, which are centered at the same position on each sensor, while reducing the mutual and parasitic coupling between them by optimizing the on-board wiring. The physics requirements are set by the installation of two high-power/high-energy neutral beam injection systems on TCV, i.e., studying fast ions physics, coherent instabilities, and turbulence in the (super-)Alfvénic frequency range. In this paper, we report the manufacturing, installation, and commissioning work for these high-frequency LTCC-3D magnetic sensors and conclude with an overview of illustrative experimental results obtained with this system. The LTCC-3D data provide new insights into the δBPOL coherent (eigenmodes, up to ∼400 kHz) and in-coherent background turbulent fluctuations in the higher frequency range up to ∼1 MHz, which were not previously available with the TCV Mirnov sensors. Furthermore, the LTCC-3D δBPOL measurements allow us to cross-check the data obtained with the standard Mirnov coils and have led to the identification of largeelectromagnetic (EM) noise pick-up for the Mirnov data acquisition (DAQ). When the sources of EM noise pick-up on the Mirnov DAQ are removed, the LTCC-3D data for δBPOL are in good overall agreement, i.e., within the expected measurement uncertainties, with those obtained with the standard Mirnov sensors located at the same poloidal position in the frequency range where the respective data acquisition overlap, routinely up to 125 kHz and up to 250 kHz in some discharges. The LTCC-3D δBPAR measurements (not previously available in TCV or elsewhere) provide evidence that certain instabilities have a finite parallel δB at the wall, hence at the LCFS, consistent with the recent theoretical results for pressure-driven modes. The LTCC-3D δBNOR measurements improve significantly on the corresponding measurements with the saddle loops, which are mounted onto the wall and have a bandwidth of ∼3 kHz (due to the wall penetration time). A detailed end-to-end system modeling tool has been developed and applied to test on the simulated data the actual measurement capabilities of this new diagnostic system and obtain the ensuing estimates of the intrinsic measurement uncertainties. A detailed error analysis is then performed so that, finally, fully calibrated, absolute measurements of the frequency-dependent amplitude and spectral breaks of coherent eigenmodes and in-coherent broadband magnetic fluctuations are provided for the first time in physical units with quantitative uncertainties.
Publication
Journal: World Neurosurgery
June/7/2019
Abstract
Few studies have addressed the causes of poor expansion of the spinal canal after open-door laminoplasty (ODL) that require revision surgery. The aim of this study is to identify the reasons of poor expansion of the spinal canal after ODL and to discuss the surgical methods and clinical outcomes of the posterior revision surgery.All patients who underwent posterior revision surgery because of poor expansion of the spinal canal after ODL were retrospectively reviewed at our spine center. Clinical data, radiologic findings, method of surgical revision, interval between surgeries, Japanese Orthopaedic Association (JOA) score, and complications were analyzed.We identified 16 patients that underwent posterior revision surgery because of poor expansion of the spinal canal after ODL. The main causes of poor expansion of the spinal canal included inadequate expansion degree of the spinal canal (75%, 12/16) and improper expansion range of the spinal canal (25%, 4/16). Revision surgery was performed with posterior ODL, laminectomy and fusion (LCF), or laminectomy of responsible lamina. The interval between the initial procedure and revision surgery was 72.2 months (range, 0.5-168 months). The mean JOA score was restored from 10.6 (range, 8-13) to 14.3 (range, 13-17) after the revision surgery.The main causes of poor expansion of the spinal canal after ODL were inadequate expansion degree of the spinal canal and improper expanded range of the spinal canal. Posterior revision surgeries, such as ODL, LCF, and laminectomy of responsible lamina, could guarantee fine clinical results.
Publication
Journal: Medicine
September/2/2020
Abstract
Introduction: Lateral condylar fracture (LCF) of the humerus in children is one of the commonest elbow injuries in children. Early recognition of the problem and appropriate management usually yields satisfactory outcomes. Closed or open reduction with Kirschner-wire (KW) is a cost-effective choice of fixation method for displaced fracture. However, various other methods, including partially threaded cannulated cancellous screw and biodegradable pin (BP), have also been used. This study aimed to investigate the efficacy of BP and compare its clinical outcomes with KW.
Material and methods: Patients with LCF admitted from January 2008 to January 2016 at our institute were reviewed retrospectively. Baseline information and clinical data were collected from Hospital Database. Patients were divided into the KW group and BP group.
Results: In all, 85 patients (male 50, female 35) in the KW group and 76 patients (male 47, female 29) in the BP group were included in this study. The average age of patients in the KW group was 5.2 years, and that of BP was 5.9 years. No nonunion or malunion was observed in either group. At the last follow-up visit, there was no statistically significant difference between the 2 groups with regard to elbow function and appearance. The incidence of long-term complications, including avascular necrosis, fishtail deformity, and lateral prominence, showed no significant difference between both the groups. The incidence of hardware prominence was higher in the KW (13/85, 15.6%) than BP (2/76, 2.6%) group (P < .001).
Conclusions: Both KW and BP are safe and effective choices for LCF of the humerus in children. Both the implant designs produce satisfactory and comparable clinical outcomes. However, BP has the advantage of less hardware prominence, no need for hardware removal, and fewer long-term complications.
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