The growth of nanotechnology has revolutionized the diagnosis and treatment of diseases, with high precision and effectiveness. Nanoparticles (NPs) represent a major point of attention in the scientific field, with an increasing number of studies revealing promising results. The unique physicochemical properties, biocompatibility, and highly developed chemical properties of gold nanoparticles (AuNPs) have promoted breakthroughs in the cancer community, focusing on the therapeutic and diagnostic applications of cancer diagnosis and treatment. This perspective aims to summarize the latest research on multifunctional AuNPs as therapeutic diagnostic agents in cancer diagnosis and treatment. Several nanostructured hybrid AuNPs have been reviewed and their applications in imaging, targeting, therapy, and delivery have been discussed.

Keywords: anti-cancer agents; cancer therapy; hybrid nanoparticles; multifunctional gold nanoparticles; nanotechnology; theranostic.