Vesicular traffic: a Rab SANDwich.
Journal: 2010/July - Current Biology
ISSN: 1879-0445
Abstract:
The small GTPases Rab5 and Rab7 mark temporally distinct but sequentially connected stages in phagosome maturation, but the mechanism underlying the transition between these stages has been unclear. Recent studies in Caenorhabditis elegans have now uncovered a new protein complex that connects Rab5 to Rab7.
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