Trilineage Dysplasia in an Adolescent With Germline GATA2 Mutation.
Journal: 2019/April - Journal of Pediatric Hematology/Oncology
ISSN: 1536-3678
Abstract:
The GATA family of DNA binding proteins consists of six different transcription factors (GATA1-6), each with diverse biologic function. The GATA2 protein has been shown to be vital for proliferation and maintenance of hematopoietic stem cells; mutations result in variable phenotypes including myelodysplastic syndrome.
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