Transcriptional regulation and transformation by Myc proteins.
Journal: 2005/August - Nature Reviews Molecular Cell Biology
ISSN: 1471-0072
PUBMED: 16064138
DOI: 10.1038/nrm1703
Abstract:
Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.
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