Synthesis of oxindoles via visible light photoredox catalysis.
Journal: 2012/April - Organic and Biomolecular Chemistry
ISSN: 1477-0539
Abstract:
2-Electron-withdrawing-group-substituted 2-bromoanilides can be converted to the corresponding 3,3-disubstituted oxindoles with high efficiency under visible light irradiation by using fac-Ir(ppy)(3) as the photoredox catalyst. This protocol is suitable for the synthesis of oxindoles with chloro and bromo atoms attached to the phenyl ring.
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