[Study on constituents of the aerial parts of Pogostemon cablin].

Journal: 2014/June - Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

ISSN: 1001-4454

Abstract:

OBJECTIVE

To investigate the chemical constituents of the aerial parts of Pogostemon cablin.

METHODS

The constituents were isolated by column chromatography over silica gel, Sephadex LH-20 and C8. Structures were identified by spectroscopic data analysis.

RESULTS

Thirteen compounds were obtained and elucidated as patchouli alcohol (1), pogostone (2), friedelin (3), epifriedelinol (4), oleanolic acid (5), methyl oleanolate (6), 5alpha-stigmast-3,6-dione (7), stigmast-4-ene-3-one (8), beta-sitosterol (9), pachypodol (10), retusin (11), (-)-guaiacylglycerol (12) and dibutyl phthalate (13).

CONCLUSIONS

Compounds 6, 7, 8, 12 and 13 are isolated from this genus for the first time.

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