Platelet activation studies with anti-CD41/61 monoclonal antibodies.
Journal: 1997/February - Veterinary Immunology and Immunopathology
ISSN: 0165-2427
PUBMED: 8896225
Abstract:
The purpose of this study was to monitor platelet activation by following alpha IIb beta 3 integrin (GpIIb/IIIa complex or CD41/CD61) on the platelet surface by flow cytometry (FCM) analysis using workshop mAbs. The results obtained with the mAbs showed increased expression of the GpIIb/IIIa complex (about 40%) on the platelet membrane surface under thrombin stimulation.
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