Peptide-cleaving catalyst selective for peptide deformylase.
+2 authors
Journal: 2005/April - Journal of the American Chemical Society
ISSN: 0002-7863
Abstract:
A peptide-cleaving catalyst selective for peptide deformylase (PDF) was obtained from a library containing about 15 000 catalyst candidates. The catalyst cleaved the polypeptide backbone of PDF at Gln(152)-Arg(153). Docking simulations suggested multiple modes of interactions in the complex formed between the catalyst and PDF.
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