Passicol, an Antibacterial and Antifungal Agent Produced by <em>Passiflora</em> Plant Species: Preparation and Physicochemical Characteristics
Abstract
An increased yield of the crude material with antibacterial and antifungal activity produced by Passiflora species was obtained by aerated bathing of cut rinds of banana passion fruit in water in rotating cylindrical bottles. The crude material was separated into several fractions by thin-layer chromatography with the use of silica gel and ethyl acetate-chloroform (2:1). The fractions showing ultraviolet absorption maxima in the vicinity of 340, 358, and 375 to 377 nm were biologically active. The data indicate that the active material, here called “Passicol” for the first time, has characteristics of the polyacetylenic group of compounds. The activity can be preserved for a long time when crude material is stored in organic solvent in the dark at 6 C. Gentle bathing of the cut rinds of Passiflora in water in the presence of air and ethylene stimulated the formation of the active principle.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- JANSEN EF, WALLACE JM. FORMATION OF BENZENE AND TOLUENE FROM ACETYLENE-14C IN THE AVOCADO. J Biol Chem. 1965 Mar;240:1042–1044. [PubMed] [Google Scholar]
- McGlasson WB, Pratt HK. Effects of Wounding on Respiration and Ethylene Production by Cantaloupe Fruit Tissue. Plant Physiol. 1964 Jan;39(1):128–132.[PMC free article] [PubMed] [Google Scholar]
- Nicolls JM, Birner J, Forsell P. Passicol, an antibacterial and antifungal agent produced by Passiflora plant species: qualitative and quantitative range of activity. Antimicrob Agents Chemother. 1973 Jan;3(1):110–117.[PMC free article] [PubMed] [Google Scholar]