Oxygen uptake by Treponema pallidum.
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Journal: 1974/September - Infection and Immunity
ISSN: 0019-9567
PUBMED: 4366918
Abstract:
Virulent Treponema pallidum has been shown to consume O(2) at a rate similar to that of the known aerobic spirochaete, Leptospira. Such O(2) uptake is cyanide sensitive, indicating a functioning cytochrome oxidase. Inhibition of O(2) uptake by azide, chlorpromazine, and amytal further suggests a functioning electron transport system for the oxidation of nicotinamide adenine dinucleotide (reduced) to O(2). Evidence is consistent with the probability that this terminal electron-transport system is coupled to oxidative phosphorylation. The potential significance of these findings is discussed.
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Infect Immun 10(1): 123-127
PMID: 4366918

Oxygen Uptake by <em>Treponema pallidum</em>

Abstract

Virulent Treponema pallidum has been shown to consume O2 at a rate similar to that of the known aerobic spirochaete, Leptospira. Such O2 uptake is cyanide sensitive, indicating a functioning cytochrome oxidase. Inhibition of O2 uptake by azide, chlorpromazine, and amytal further suggests a functioning electron transport system for the oxidation of nicotinamide adenine dinucleotide (reduced) to O2. Evidence is consistent with the probability that this terminal electron-transport system is coupled to oxidative phosphorylation. The potential significance of these findings is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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Department of Microbiology, University of Massachusetts, Amherst, Massachusetts 01002
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Abstract
Virulent Treponema pallidum has been shown to consume O2 at a rate similar to that of the known aerobic spirochaete, Leptospira. Such O2 uptake is cyanide sensitive, indicating a functioning cytochrome oxidase. Inhibition of O2 uptake by azide, chlorpromazine, and amytal further suggests a functioning electron transport system for the oxidation of nicotinamide adenine dinucleotide (reduced) to O2. Evidence is consistent with the probability that this terminal electron-transport system is coupled to oxidative phosphorylation. The potential significance of these findings is discussed.
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