Abstract:

Kellogg, Douglas S., Jr. (Communicable Disease Center, Atlanta, Ga.), William L. Peacock, Jr., W. E. Deacon, L. Brown, and Carl I. Pirkle. Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation. J. Bacteriol. 85:1274-1279. 1963.-One type, obtained from the purulent exudate of acute gonorrhea was maintained by 69 selective in vitro passages, at which point the organisms produced infections in human volunteers. A predominance of clonal types found in laboratory strains and a lack of ability to infect human volunteers resulted from 69 nonselective in vitro passages. Physiological and serological characteristics of the clonal types are compared. We are now in a position to study Neisseria gonorrhoeae organisms in their virulent form.

Open in

PUBMED | PMC | Google Scholar | Wikipedia

Relations:

Content

Citations

(622)

References

(3)

Diseases

(1)

Organisms

(2)

Processes

(1)

Anatomy

(1)

<em>NEISSERIA GONORRHOEAE</em> I.

Abstract

Kellogg, Douglas S., Jr. (Communicable Disease Center, Atlanta, Ga.), William L. Peacock, Jr., W. E. Deacon, L. Brown, and Carl I. Pirkle. Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation. J. Bacteriol. 85:1274–1279. 1963.—One type, obtained from the purulent exudate of acute gonorrhea was maintained by 69 selective in vitro passages, at which point the organisms produced infections in human volunteers. A predominance of clonal types found in laboratory strains and a lack of ability to infect human volunteers resulted from 69 nonselective in vitro passages. Physiological and serological characteristics of the clonal types are compared. We are now in a position to study Neisseria gonorrhoeae organisms in their virulent form.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.6M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Image
on p.1276

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

DEACON WE, PEACOCK WL, Jr, FREEMAN EM, HARRIS A. Identification of Neisseria gonorrhoeae by means of fluorescent antibodies. Proc Soc Exp Biol Med. 1959 Jun;101(2):322–325. [PubMed] [Google Scholar]
Morton HE, Shoemaker J. The Identification of Neisseria gonorrhoeae by Means of Bacterial Variation and the Detection of Small Colony Forms in Clinical Material. J Bacteriol. 1945 Nov;50(5):585–587.[PMC free article] [PubMed] [Google Scholar]
SCHERP HW. Neisseria and neisserial infections. Annu Rev Microbiol. 1955;9:319–334. [PubMed] [Google Scholar]

Venereal Disease Research Laboratory, Venereal Disease Branch, Communicable Disease Center, U.S. Public Health Service, Atlanta, Georgia

Copyright notice

Abstract

Kellogg, Douglas S., Jr. (Communicable Disease Center, Atlanta, Ga.), William L. Peacock, Jr., W. E. Deacon, L. Brown, and Carl I. Pirkle. Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation. J. Bacteriol. 85:1274–1279. 1963.—One type, obtained from the purulent exudate of acute gonorrhea was maintained by 69 selective in vitro passages, at which point the organisms produced infections in human volunteers. A predominance of clonal types found in laboratory strains and a lack of ability to infect human volunteers resulted from 69 nonselective in vitro passages. Physiological and serological characteristics of the clonal types are compared. We are now in a position to study Neisseria gonorrhoeae organisms in their virulent form.

Collaboration tool especially designed for Life Science professionals.Drag-and-drop any entity to your messages.

Learn More