Label-free biosensing with single-molecule force spectroscopy.
Journal: 2013/September - Chemical Communications
ISSN: 1364-548X
PUBMED: 23486781
DOI: 10.1039/c3cc40506k
Abstract:
We demonstrate here a novel single-molecule, label-free bioanalytical system capable of sensing the presence of specific ssDNA oligomer sequences and proteins with high selectivity and sensitivity. An ssDNA concentration of 1 nM and a Lyz concentration of 0.65 nM could be detected.
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