Ethno-botanical explorations with regard to the folk-lore medicine in Coimbatore district of Tamil Nadu and Palghat district of Kerala for jaundice was carried out. Out of twenty remedies thus gathered two are found to be new reports and a few others have got interesting combination. The specimens are identified at Botanical Survey of India, Coimbatore and deposited in the Herbarium of Ethnobiology department of International Institute of Ayurveda, Coimbatore. Two newly reported plants for Jaundice namely Alysicarpus vaginalis DC. and Justicia tranquebariensis L. f, have been taken for phytochemical screening and pharmacological studies. The botanical name of the plant, local name, Sanskrit name and the part of the plant employed are given in table I.