Fatal varicella associated with selective natural killer cell deficiency.
Journal: 2005/April - Journal of Pediatrics
ISSN: 0022-3476
PUBMED: 15756234
Abstract:
A 2-year-old girl with recurrent severe varicella infections had a fatal outcome. Studies of cellular and humoral immunity were normal. No natural killer (NK) cells were detected, and NK activity was markedly decreased. The interleukin (IL)15/IL15R signaling pathway was intact. This case emphasizes the role of NK cells in controlling herpes viral infection.
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