Expression of FGFs during early mouse tongue development.
Journal: 2017/May - Gene Expression Patterns
ISSN: 1872-7298
Abstract:
The fibroblast growth factors (FGFs) constitute one of the largest growth factor families, and several ligands and receptors in this family are known to play critical roles during tongue development. In order to provide a comprehensive foundation for research into the role of FGFs during the process of tongue formation, we measured the transcript levels by quantitative PCR and mapped the expression patterns by in situ hybridization of all 22 Fgfs during mouse tongue development between embryonic days (E) 11.5 and E14.5. During this period, Fgf5, Fgf6, Fgf7, Fgf9, Fgf10, Fgf13, Fgf15, Fgf16 and Fgf18 could all be detected with various intensities in the mesenchyme, whereas Fgf1 and Fgf2 were expressed in both the epithelium and the mesenchyme. Our results indicate that FGF signaling regulates tongue development at multiple stages.
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Immunology 151(1): 16-25

Retinoic acid‐inducible gene I (<span style="fixed-case">RIG</span>‐I)‐like receptors (<span style="fixed-case">RLR</span>s) in fish: current knowledge and future perspectives

State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China
College of Fisheries, Jimei University, Xiamen, Fujian, China
Pin Nie, Email: nc.ca.bhi@einnip, moc.liamtoh@hsifeinp.
Corresponding author.
Correspondence: Prof. Pin Nie, State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei 430072, China. Emails: nc.ca.bhi@einnip and moc.liamtoh@hsifeinp,
Senior author: Pin Nie
Received 2016 Nov 1; Revised 2016 Dec 20; Accepted 2017 Jan 12.

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