Double bond isomers of cloprostenol.
Journal: 1980/January - Prostaglandins
ISSN: 0090-6980
PUBMED: 504688
Abstract:
The syntheses of five compounds isomeric with the potent luteolytic agent cloprostenol are described. These are the trans-delta 5, cis and trans-delta 4, cis-delta 6 (methyl ester) and cis-delta 13 analogues. The cis-delta 4 isomer is as potent as cloprostenol as a luteolytic agent in hamsters but the others are markedly less so.
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