OBJECTIVE

To study the chemical constituents from the roots of Rehmannia glutinosa.

METHODS

The compounds were isolated by various chromatographic methods and identified by spectroscopic analysis.

RESULTS

Twelve compounds were isolated and their structures were identified as 5-hydroxymethyl-pyrrole-2-carbaldehyde (1), 5-hydroxymethyl furfural (2), tyrosol (3), 5,6-dihydroxy-beta-ionone (4), 6-O-E-feruloyl ajugol (5), acteoside (6), leucosceptoside A (7), martynoside (8), isomartynoside (9), purpureaside C (10), jionoside A1 (11), and jionoside B1 (12).

CONCLUSIONS

Compounds 1, 3 and 9 were isolated from the genus Rehmannia for the first time.