Antiinflammatory, Analgesic and Antipyretic Effects of Various Plant Extracts and a Combination Thereof in Animal Models. The three main components comprising the efficacy of non-steroidal antiinflammatory drugs could be demonstrated for STW 1 in different animal models. The phytotherapeutic preparation, containing three individual plant extracts (Populus tremula, Solidago virgaurea, Fraxinus excelsior) produced dose-dependent antiinflammatory, analgesic and antipyretic effects which were similar to those of the reference substances salicyl alcohol and indometacin. As each of the individual extracts displayed considerable efficacy, it may be assumed that each of them contributes to the overall effects of the combination STW 1.