Last Verified: | May/31/2020 |
First Submitted: | April/23/2020 |
Estimated Enrollment Submitted: | April/23/2020 |
First Posted: | April/26/2020 |
Last Update Submitted: | June/12/2020 |
Last Update Posted: | June/15/2020 |
Actual Study Start Date: | May/31/2020 |
Estimated Primary Completion Date: | December/30/2020 |
Estimated Study Completion Date: | June/29/2021 |
Study Type: | Observational |
Observational Model: | Cohort |
Time Perspective: | Cross-Sectional |
Arm | Intervention/treatment |
---|---|
Infertile PCOS women All Vietnamese, infertile women, diagnosed with PCOS according to the Rotterdam criteria (2003) at IVFMD Tan Binh and IVFMD Phu Nhuan will be enrolled to the study. | Diagnostic Test: Infertile PCOS women Oral glucose tolerance test with 75 g glucose (75 g OGTT) will be performed to those with normal fasting glucose and HbA1C levels. Women will be recommended to have normal diet for 3 days and overnight fasting for at least 8 hours. The blood withdrawal will be performed twice: (i) fasting and (2i) 2 hours after solution administration. The volume of blood for each test is 2 ml. Impaired glucose tolerance will be diagnosed when two-hour glucose levels of 140 to 199 mg/dL (7.8 to 11.0 mmol/l) (American Diabetes Association, 2018). |
Ages Eligible for Study: | 18 Years to 18 Years |
Sexes Eligible for Study: | Female |
Sampling method: | Non-Probability Sample |
Accepts Healthy Volunteers: | Yes |
Criteria: | Inclusion Criteria: - Vietnamese infertile women with polycystic ovarian syndrome diagnosed followed by Rotterdam criteria (2003) Exclusion Criteria: - Endocrinal abnormalities including thyroid-stimulating hormone (TSH) >5mIU/mL, serum prolactin (PRL) >30ng/mL and any other concomitant endocrinopathy such as a history of hypothyroidism, Cushing's syndrome, premature ovarian insufficiency and late-onset or non-classic congenital adrenal hyperplasia will be excluded. - Women who were already diagnosed as diabetes by endocrinologists |