Herbal intake is escalating worldwide. To the best of our knowledge, myocardial infarction (MI) has not been reported following ingestion of laxative herbs in the absence of the well known risk factors for MI. We report on a 45- yr-old female patient who sustained acute inferior MI 8 h following Cassia italica ingestion. Subsequently, cardiac catheterization revealed patent coronary arteries. We assume that, in this case, MI may partly be related herbal ingestion. Further studies and public awareness of this complication in certain communities are needed.