Can <em>Glycyrrhiza glabra</em> L. reduce both upper gastrointestinal tract bleeding and ventilator‐associated pneumonia in intensive‐care unit patients?

Abolfazl Firouzian

Hadi Khezri

^{Department of Anesthesiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari Iran,}

^{Thalassemia Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari Iran,}

Abolfazl Firouzian, Email: moc.liamg@naizuorif.bA.

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Abolfazl Firouzian, Email: moc.liamg@naizuorif.bA.

Hadi Darvishi Khezri, Email: moc.oohay@78ihsivradidaH.

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References

1. Mohebbi L, Hesch K. Stress ulcer prophylaxis in the intensive care unit. Proc (Bayl Univ Med Cent) 2009; 22: 373–6.
2. Kuo F‐C, Wu D‐C. Stress ulcer prophylaxis in the intensive care unit. Adv Digest Med 2014; 1: 36–37. [PubMed]
3. Darvishi Khezri H, Gorji MAH, Morad A, Gorji H. Comparison of the antibacterial effects of matrica & Persica and chlorhexidine gluconate mouthwashes in mechanically ventilated ICU patients: a double blind randomized clinical trial. Rev Chilena Infectol 2013; 30: 368–73. [[PubMed]
4. Khorvash F, Abbasi S, Meidani M et alThe comparison between proton pump inhibitors and sucralfate in incidence of ventilator associated pneumonia in critically ill patients. Adv Biomed Res 2014; 3: 12–22.
5. Alhazzani W, Alshahrani M, Moayyedi P et alStress ulcer prophylaxis in critically ill patients: review of the evidence. Pol Arch Med Wewn 2012; 122: 107–14. [[PubMed]
6. Messori A, Trippoli S, Vaiani M et alBleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta‐analysis of randomised controlled trials. BMJ 2000; 321: 1103–6.
7. Gupta VK, Fatima A, Faridi U et alAntimicrobial potential of Glycyrrhiza glabra roots. J Ethnopharmacol 2008; 116: 377–80. [[PubMed]
8. Rahnama M, Mehrabani D, Japoni S et alThe healing effect of licorice (Glycyrrhiza glabra) on Helicobacter pylori infected peptic ulcers. J Res Med Sci 2013; 18: 532–3.
9. Asl MN, Hosseinzadeh H. Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytother Res 2008; 22: 709–24.
10. Szweda M, Szarek J, Dublan K et alEffect of mucoprotective plant‐derived therapies on damage to colonic mucosa caused by carprofen and robenacoxib administered to healthy dogs for 21 days. Vet Q 2014; 34: 185–93. [[PubMed]
11. Sancar M, Hantash T, Okuyan B et alComparative effectiveness of Glycyrrhiza glabra vs. omeprazole and misoprostol for the treatment of aspirin‐induced gastric ulcers. Afr J Pharm Pharacol 2009; 3: 615–20. [PubMed]
12. Ligha A, Fawehinmi H. Protection by liquorice in alcohol induced gastric mucosa damage. Pak J Nutr 2009; 8: 1532–6. [PubMed]
13. Meletis CD, Zabriskie N. Natural approaches for gastroesophageal reflux disease and related disorders. Altern Complement Ther 2007; 13: 64–70. [PubMed]
14. Fukai T, Marumo A, Kaitou K et alAntimicrobial activity of licorice flavonoids against methicillin‐resistant Staphylococcus aureus. Fitoterapia 2002; 73: 536–9. [[PubMed]
15. Arora DS, Kaur GJ. Antibacterial activity of some Indian medicinal plants. J Nat Med 2007; 61: 313–17. [PubMed]
16. Fiore C, Eisenhut M, Krausse R et alAntiviral effects of Glycyrrhiza species. Phytother Res 2008; 22: 141–8.
17. De Smet A, Kluytmans JA, Cooper BS et alDecontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med 2009; 360: 20–31. [[PubMed]
18. Li H‐E, Qiu J‐Z, Yang Z‐Q et alGlycyrrhetinic acid protects mice from Staphylococcus aureus pneumonia. Fitoterapia 2012; 83: 241–8. [[PubMed]