Aldo-Keto Reductase family 1 member B10 (AKR1B10) is an enzyme of the aldo-keto reductase superfamily, and catalyzes the reduction of aliphatic and aromatic aldehydes. AKR1B10 is commonly expressed in adrenal glands, the small intestine and colon tissues. AKR1B10 staining is useful in the recognition of liver carcinogenesis.