Affinity Biosciences
BF0392
$250.00
50μl
| 50μl - | $250.00 | |
| 100μl - | $350.00 | |
| 200μl - | $450.00 |
4E-BP1 Antibody
Figure 1: Western blot analysis using 4E-BP1 mouse mAb against truncated 4E-BP1 recombinant protein（1）and...Antigen:
Eukaryotic translation initiation factor 4E-binding protein 1
Synonyms: Phosphorylated heat- and acid-stable protein regulated by insulin 1; 4EBP1_HUMAN; B2R502; D3DSW8; Q13541; Q6IBN3
Host:Mouse
Reactivity:Human
Application:Western Blotting; Immunohistochemistry; ELISA
Isotype:IgG1
Clonality:Monoclonal
Aliases:4E-BP1; 4EBP1; 4EBP1_HUMAN; BP 1; eIF4E binding protein 1; eIF4E-binding protein 1; Eif4ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; PHASI; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Description:
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Purification:Affinity-chromatography.
Concentration:1mg/ml
Buffer form:Liquid
Storage buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt
Specificity:
4E-BP1 antibody detects endogenous levels of total 4E-BP1.
Storage conditions:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Product specifications
Product specifications
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