Abbkine Scientific Co., Ltd.
ABP54082
$100.00
30μl
| 30μl - | $100.00 | |
| 100μl - | $220.00 | |
| 200μl - | $360.00 |
4E-BP1 Polyclonal Antibody
Antigen:
Eukaryotic translation initiation factor 4E-binding protein 1
Synonyms: Phosphorylated heat- and acid-stable protein regulated by insulin 1; 4EBP1_HUMAN; B2R502; D3DSW8; Q13541; Q6IBN3
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; IHC-P; ELISA
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:
EIF4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1
4E-BP1
eIF4E-binding protein 1
Phosphorylated heat- and acid-stable protein regulated by insulin 1
PHAS-I
Buffer form:PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Synthesized peptide derived from human 4E-BP1 around the non-phosphorylation site of T37.
Usage:
EIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
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