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0.1ml C
IHC413-1000.1ml C -$210.00
IHC413-11ml C -$980.00
IHC413-77ml P -$520.00
RIDACOM Ltd. hotline:
Serine/arginine repetitive matrix protein 4
Synonyms: Medulloblastoma antigen MU-MB-2.76; Neural-specific serine/arginine repetitive splicing factor of 100 kDa; SRRM4_HUMAN; A7MD48; A8K5P6; B2RZH7; Q7Z5F0; Q96JH4
Serine/Arginine Repetitive Matrix 4 (SRRM4), also known as nSR100, is a vertebrate- and neural-specific Ser/Arg repeat-related protein that acts in the brain as a key regulator of alternative splicing. nSR100 has been identified as an activator of the small cell lung cancer-specific isoform of RE1-silencing transcription factor. The protein is involved in the progression of neuroendocrine prostate cancer, an aggressive subtype of castration-resistant prostate cancer, and has been suggested as a potential therapeutic target. A correlation has been made between underexpression of the SRRM4 protein and autism spectrum disorders.
Positive control:Cerebellum
Dilution range:1:100 - 1:200
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