Name: TTF-1 Antibody
Brand: Affinity Biosciences
Price: 250 USD

AF4733

$250.00

50μl

	50μl -	$250.00
	100μl -	$350.00
	200μl -	$450.00

RIDACOM Ltd. hotline:

+3592 955 99 98

info@ridacom.com

TTF-1 Antibody

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Western blot analysis of TTF-1 in lysates of H441, using TTF-1 Antibody(AF4733).

Antigen:

Homeobox protein Nkx-2.1

Synonyms: Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; Thyroid-specific enhancer-binding protein; NKX21_HUMAN; D3DSA3; O14954; O14955; P43699; Q7KZF6; Q9BRJ8

BioSeek|Uniprot

Host:Rabbit

Reactivity:Human; Mouse; Rat

Application:Western Blotting; ELISA

Isotype:IgG

Clonality:Polyclonal

Aliases:AV026640; BCH; Benign chorea; BHC; Homeobox protein NK 2 homolog A; Homeobox protein NK-2 homolog A; Homeobox protein Nkx 2.1; Homeobox protein Nkx-2.1; Homeobox protein Nkx2.1; NK 2; NK 2 homolog A; NK2; NK2 homeobox 1; NK2, drosophila, homolog of, A; NK2.1, mouse, homolog of; Nkx 2 1; NKX 2.1; NKX 2A; NKX2 1; Nkx2-1; NKX2.1; NKX21_HUMAN; NKX2A; T EBP; T/EBP; TEBP; Thyroid nuclear factor 1; Thyroid nuclear factor; Thyroid specific enhancer binding protein; Thyroid transcription factor 1; Tin man; Tinman; TITF 1; TITF1; TTF 1; TTF-1; TTF1

Description:

Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

Purification:The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Concentration:1mg/ml

Buffer form:Liquid

Storage buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt

Specificity:

TTF-1 Antibody detects endogenous levels of TTF-1.

Storage conditions:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Product specifications