Name: TNFRSF11B Antibody
Brand: Affinity Biosciences
Price: 280 USD

DF6824

$280.00

100μl

	100μl -	$280.00
	200μl -	$350.00

RIDACOM Ltd. hotline:

+3592 955 99 98

info@ridacom.com

TNFRSF11B Antibody

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Western blot analysis of extracts from Mouse heart, using TNFRSF11B Antibody. The lane on the left...

https://d1vffmuvmgkypt.cloudfront.net/image/ridacom_ltd/affinity_biosciences/PRODUCT_SOURCE__AFFINITY__SUPPLIER__RIDACOM__ID__DF6824__1

Western blot analysis of K562 whole cell lysates, using TNFRSF11B Antibody. The lane on the left...

https://d1vffmuvmgkypt.cloudfront.net/image/ridacom_ltd/affinity_biosciences/PRODUCT_SOURCE__AFFINITY__SUPPLIER__RIDACOM__ID__DF6824__2

DF6824 at 1/100 staining Mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat...

Antigen:

Tumor necrosis factor receptor superfamily member 11B

Synonyms: Osteoclastogenesis inhibitory factor; Osteoprotegerin; TR11B_HUMAN; B2R9A8; O00300; O60236; Q53FX6; Q9UHP4

BioSeek|Uniprot

Host:Rabbit

Reactivity:Human; Mouse; Rat

Application:Western Blotting; Immunohistochemistry; ELISA

Isotype:IgG

Clonality:Polyclonal

Aliases:MGC29565; OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNF receptor superfamily member 11b; TNFRSF 11B; TNFRSF11B; TR 1; TR1; TR11B_HUMAN; Tumor necrosis factor receptor superfamily member 11B

Description:

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

Purification:The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Concentration:1mg/ml

Buffer form:Liquid

Storage buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt

Specificity:

TNFRSF11B Antibody detects endogenous levels of total TNFRSF11B.

Storage conditions:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Product specifications