Affinity Biosciences
BF0156
$250.00
50μl
| 50μl - | $250.00 | |
| 100μl - | $350.00 | |
| 200μl - | $450.00 |
TNFRSF11B Antibody
Figure 1: Western blot analysis using TNFRSF11B mAb against HEK293 (1) and TNFRSF11B(AA: 22-401)-hIgGFc...Antigen:
Tumor necrosis factor receptor superfamily member 11B
Synonyms: Osteoclastogenesis inhibitory factor; Osteoprotegerin; TR11B_HUMAN; B2R9A8; O00300; O60236; Q53FX6; Q9UHP4
Host:Mouse
Reactivity:Human
Application:Western Blotting; ELISA; FCM
Isotype:IgG1
Clonality:Monoclonal
Aliases:MGC29565; OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNF receptor superfamily member 11b; TNFRSF 11B; TNFRSF11B; TR 1; TR1; TR11B_HUMAN; Tumor necrosis factor receptor superfamily member 11B
Description:
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Purification:Affinity-chromatography.
Concentration:1mg/ml
Buffer form:Liquid
Storage buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt
Specificity:
TNFRSF11B antibody detects endogenous levels of total TNFRSF11B.
Storage conditions:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Product specifications
Product specifications
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