Affinity Biosciences
BF0086
$250.00
50μl
| 50μl - | $250.00 | |
| 100μl - | $350.00 | |
| 200μl - | $450.00 |
SERPINE1 Antibody
Figure 1: Western blot analysis using SERPINE1 mAb against human SERPINE1 (AA: 194-316) recombinant...Antigen:
Plasminogen activator inhibitor 1
Synonyms: Endothelial plasminogen activator inhibitor; Serpin E1; PAI1_HUMAN; B7Z4S0; F8WD53; P05121
Host:Mouse
Reactivity:Human
Application:Western Blotting; Immunohistochemistry; ELISA; FCM
Isotype:IgG1
Clonality:Monoclonal
Aliases:Clade E; Endothelial plasminogen activator inhibitor; Nexin; PAI 1; PAI; PAI-1; PAI1_HUMAN; PLANH1; Plasminogen activator inhibitor 1; Plasminogen activator inhibitor type 1; Serine (or cysteine) proteinase inhibitor; Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1; Serpin E1; Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1; Serpin peptidase inhibitor clade E; Serpine 1; SERPINE1
Description:
Serine protease inhibitor. Inhibits TMPRSS7 (PubMed:15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots (PubMed:8481516, PubMed:9207454, PubMed:17912461). As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading (PubMed:9175705). Acts as a regulator of cell migration, independently of its role as protease inhibitor (PubMed:15001579, PubMed:9168821). It is required for stimulation of keratinocyte migration during cutaneous injury repair (PubMed:18386027). It is involved in cellular and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (PubMed:25808697, PubMed:27046084).
Purification:Affinity-chromatography.
Concentration:1mg/ml
Buffer form:Liquid
Storage buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt
Specificity:
SERPINE1 antibody detects endogenous levels of total SERPINE1.
Storage conditions:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Product specifications
Product specifications
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