Affinity Biosciences
AF3446
$280.00
100μl
| 100μl - | $280.00 | |
| 200μl - | $350.00 |
Phospho-PPAR-BP (Thr1457) Antibody
Western blot analysis of Phospho-PPAR-BP (Thr1457) expression in various lysates
AF3446 at 1/100 staining human Breast carcinoma tissue sections by IHC-P. The tissue was formaldehyde...
AF3446 staining HuvEc by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton...
Antigen:
Mediator of RNA polymerase II transcription subunit 1
Synonyms: Activator-recruited cofactor 205 kDa component; Mediator complex subunit 1; Peroxisome proliferator-activated receptor-binding protein; Thyroid hormone receptor-associated protein complex 220 kDa component; Thyroid receptor-interacting protein 2; Vitamin D receptor-interacting protein complex component DRIP205; p53 regulatory protein RB18A; MED1_HUMAN; A2RRQ6; O43810; O75447; Q15648; Q6P9H7; Q6PK58; Q9HD39
Host:Rabbit
Reactivity:Human; Mouse
Application:Western Blotting; Immunohistochemistry; ELISA
Isotype:IgG
Clonality:Polyclonal
Aliases:Activator-recruited cofactor 205 kDa component; ARC205; CRSP1; CRSP200; DRIP205; DRIP230; MED1; MED1_HUMAN; Mediator complex subunit 1; Mediator of RNA polymerase II transcription subunit 1; p53 regulatory protein RB18A; PBP; Peroxisome proliferator-activated receptor-binding protein; PPAR binding protein; PPAR-binding protein; PPARBP; PPARGBP; RB18A; Thyroid hormone receptor-associated protein complex 220 kDa component; Thyroid receptor-interacting protein 2; TR-interacting protein 2; Trap220; TRIP-2; TRIP2; Vitamin D receptor-interacting protein complex component DRIP205
Description:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).
Purification:The antibody is from purified?rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Concentration:1mg/ml
Buffer form:Liquid
Storage buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt
Specificity:
Phospho-PPAR-BP (Thr1457) Antibody detects endogenous levels of PPAR-BP only when phosphorylated at Threonine 1457.
Storage conditions:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Product specifications
Product specifications
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