Name: Phospho-PDCD4 (Ser457) Antibody
Brand: Affinity Biosciences
Price: 280 USD

AF3465

$280.00

100μl

	100μl -	$280.00
	200μl -	$350.00

RIDACOM Ltd. hotline:

+3592 955 99 98

info@ridacom.com

Phospho-PDCD4 (Ser457) Antibody

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Western blot analysis of PDCD4 phosphorylation expression in serum treated Hela whole cell lysates,The...

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Phospho-PDCD4 (Ser457) Antibody for IHC in human colon tissue

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AF3465 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton...

Antigen:

Programmed cell death protein 4

Synonyms: Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a; PDCD4_HUMAN; B2RCV4; B5ME91; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834

BioSeek|Uniprot

Host:Rabbit

Reactivity:Human; Mouse; Rat

Application:Western Blotting; Immunohistochemistry; ELISA

Isotype:IgG

Clonality:Polyclonal

Aliases:Death up-regulated gene protein; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor; Neoplastic transformation inhibitor protein; Nuclear antigen H731; Nuclear antigen H731 like; Nuclear antigen H731 like protein; Nuclear antigen H731-like; PDCD 4; Pdcd4; PDCD4_HUMAN; Programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; Tis; Topoisomerase-inhibitor suppressed protein

Description:

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

Purification:The antibody is from purified?rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Concentration:1mg/ml

Buffer form:Liquid

Storage buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt

Specificity:

Phospho-PDCD4 (Ser457) Antibody detects endogenous levels of PDCD4 only when phosphorylated at Serine 457.

Storage conditions:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Product specifications