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Affinity Biosciences
AF2002
$280.00
100μl
100μl -$280.00
200μl -$350.00
RIDACOM Ltd. hotline:
Phospho-I kappaB alpha (Ser32/Ser36) Antibody
Antigen:
NF-kappa-B inhibitor alpha
Synonyms: I-kappa-B-alpha; Major histocompatibility complex enhancer-binding protein MAD3; IKBA_HUMAN; B2R8L6; P25963
BioSeek|Uniprot
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; Immunohistochemistry; ELISA
Isotype:IgG
Clonality:Polyclonal
Aliases:I kappa B alpha; I-kappa-B-alpha; IkappaBalpha; IkB-alpha; IKBA; IKBA_HUMAN; IKBalpha; MAD 3; MAD3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappa-B inhibitor alpha; NFKBI; NFKBIA; Nuclear factor of kappa light chain gene enhancer in B cells; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha
Description:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Purification:The antibody is from purified?rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Concentration:1mg/ml
Buffer form:Liquid
Storage buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt
Specificity:
Phospho-I kappaB- alpha (Ser32/Ser36) Antibody detects endogenous levels of I kappaB- alpha only when phosphorylated at Serine 32/Serine 36.
Storage conditions:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
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