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Affinity Biosciences
AF3466
$280.00
100μl
100μl -$280.00
200μl -$350.00
RIDACOM Ltd. hotline:
Phospho-FRS2 (Tyr436) Antibody
Antigen:
Fibroblast growth factor receptor substrate 2
Synonyms: FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; FRS2_HUMAN; B0LPF2; B2R684; O43558; Q7LDQ6; Q8WU20
BioSeek|Uniprot
Host:Rabbit
Reactivity:Human; Mouse
Application:Western Blotting; Immunohistochemistry; ELISA
Isotype:IgG
Clonality:Polyclonal
Aliases:FGFR signaling adaptor SNT; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; Fibroblast growth factor receptor substrate 2; FRS 2; FRS2; FRS2_HUMAN; FRS2A; FRS2alpha; SNT 1; SNT; SNT-1; SNT1; Suc 1 Associated Neurotrophic Factor Target; Suc1 associated neurotrophic factor target 1; Suc1-associated neurotrophic factor target 1
Description:
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Purification:The antibody is from purified?rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Concentration:1mg/ml
Buffer form:Liquid
Storage buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt
Specificity:
Phospho-FRS2 (Tyr436) Antibody detects endogenous levels of FRS2 only when phosphorylated at Tyrosine 436.
Storage conditions:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
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