Name: FAS Antibody
Brand: Affinity Biosciences
Price: 250 USD

BF0557

$250.00

50μl

	50μl -	$250.00
	100μl -	$350.00
	200μl -	$450.00

RIDACOM Ltd. hotline:

+3592 955 99 98

info@ridacom.com

FAS Antibody

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Western blot analysis using FAS mouse mAb against Hela (1), Jurkat (2) cell lysate....

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Not available

Antigen:

Tumor necrosis factor receptor superfamily member 6

Synonyms: Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; TNR6_HUMAN; A9UJX4; B6VNV4; P25445; Q14292; Q14293; Q14294; Q14295; Q16652; Q5T9P1; Q5T9P2; Q5T9P3; Q6SSE9

BioSeek|Uniprot

Host:Mouse

Reactivity:Human

Application:Western Blotting; ELISA; FCM

Isotype:IgG1

Clonality:Monoclonal

Aliases:ALPS 1A; ALPS1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo-1 antigen; APO1; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen FAS; Apoptosis-mediating surface antigen FAS; APT 1; APT1; CD 95; CD 95 antigen; CD95; CD95 antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; Fas (TNF receptor superfamily, member 6); FAS 1; FAS 827dupA; Fas AMA; Fas; FAS Antigen; Fas cell surface death receptor; FAS1; FASLG receptor; FASTM; sFAS; Surface antigen APO1; TNF receptor superfamily, member 6; TNFRSF 6; TNFRSF6; TNR6_HUMAN; Tumor necrosis factor receptor superfamily member 6

Description:

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Purification:Affinity-chromatography.

Concentration:1mg/ml

Buffer form:Liquid

Storage buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt

Specificity:

FAS antibody detects endogenous levels of total FAS.

Storage conditions:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Product specifications